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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 4091-4100 of 8170

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  • Locations: Rochester, MN
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  1. Assessing the Efficacy of Steroid Treatment of Achalasia

    Rochester, MN

  2. Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab Therapy

    Rochester, MN

  3. Optimizing the Use of Ketamine to Reduce Chronic Postsurgical Pain

    Rochester, MN

  4. A Study to Evaluate Ketamine to Treat Chronic Neuropathic Pain in Patients with Traumatic Brachial Plexus Injuries

    Rochester, MN

  5. A Study to Evaluate Lasofoxifene versus Fulvestrant in Advanced or Metastatic ER+/HER2− Breast Cancer Patients with an ESR1 Mutation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study of Endovascular Biopsy and Endothelial Cell Gene Analysis in Endovascular Procedures

    Rochester, MN

  7. Dual-plane Ultrasound Imaging During Vascular Access Procedures

    Rochester, MN

  8. A Study to Evaluate the da Vinci® Xi™ Surgical System in Nipple Sparing Mastectomy (NSM) Procedures

    Rochester, MN, Jacksonville, FL

  9. Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

    Rochester, MN, Scottsdale/Phoenix, AZ

  10. Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients with Pancreatic Cancer That Has Been Removed by Surgery

    Jacksonville, FL, Rochester, MN

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