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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 47 for

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  1. HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL, La Crosse, WI, Eau Claire, WI, Mankato, MN, Albert Lea, MN

  2. ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

    Rochester, MN

  5. Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

    Jacksonville, FL

  6. Reduced Dose Hypofractionated Radiotherapy For Indolent Non-hodgkin Lymphoma

    Jacksonville, FL, Rochester, MN, Scottsdale/Phoenix, AZ, Albert Lea, MN, Eau Claire, WI, La Crosse, WI, Mankato, MN

  7. A Study to Compare Optimal MRI Timing for Pre-surgical Planning to LINAC-based Therapy

    Rochester, MN

  8. Radiation Dermatitis In Breast Cancer Patients

    Rochester, MN

  9. A Study to Evaluate the Adaptive Image Receive (AIR) Coil System for Patients Undergoing MR Imaging Simulation

    Rochester, MN

  10. Fertility Outcomes in Lymphoma Patients

    Jacksonville, FL

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