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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 91-100 of 382 for

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  1. Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia

  2. Study of the Incidence of Electrographic Status Epilepticus and Seizures of PICU Patients at National Children’s Hospital in Hanoi, Vietnam.

    Rochester, MN

  3. A Novel Approach to Infantile Spasms

    Rochester, MN

  4. Glasses for Adolescent Delayed Sleep-Wake Phase Disorder (GLAD)

    Rochester, MN

  5. A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

    Rochester, MN

  6. A Study of a Therapeutic Video Game for Social Anxiety in Children

    Rochester, MN

  7. A Study to Assess Cisplatin and Combination Chemotherapy in Treating Children and Young Adults with Hepatoblastoma or Liver Cancer After Surgery

    Rochester, MN

  8. Pneumococcal Vaccines in Patients With Asthma

    Rochester, MN

  9. A Study to Evaluate the Performance of an Advanced Algorithm with CGM in Adults, Adolescents, and Pediatrics

    Rochester, MN

  10. Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents

    Rochester, MN

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