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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 2151-2160 of 10655

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  1. Risk-Based Therapy in Treating Younger Patients with Newly Diagnosed Liver Cancer

    Rochester, MN

  2. Veliparib with or without Carboplatin in Treating Patients with Stage III or Stage IV Breast Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. Shared Decision Making in the Emergency Department: Chest Pain Choice Trial

    Rochester, MN

  4. Safety and Efficacy of Simtuzumab (GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)

    Scottsdale/Phoenix, AZ

  5. Molecular Breast Imaging in Women with Atypia and LCIS

    Rochester, MN

  6. ABSORB III Randomized Controlled Trial (RCT)

    Rochester, MN

  7. A Study of the Implementation, Safety, and Outcomes of OB Nest Model of Care for Expectant Mothers

    Rochester, MN

  8. Vinorelbine Tartrate and Cyclophosphamide in Combination with Bevacizumab or Temsirolimus in Treating Patients with Recurrent or Refractory Rhabdomyosarcoma

  9. Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients with Uncontrolled Asthma

    Rochester, MN

  10. Electronic Patient Reporting of Symptoms During Cancer Treatment

    La Crosse, WI, Eau Claire, WI, Mankato, MN

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