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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1861-1870 of 10640

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  1. A Phase 1/2, Open-label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination With Durvalumab Versus Nivolumab Monotherapy in Subjects With Select Advanced Malignancies

    Rochester, MN

  2. A Study of Crenezumab in Participants With Mild to Moderate Alzheimer Disease

    Scottsdale/Phoenix, AZ

  3. Mitral Implantation of TRAnscatheter vaLves

    Rochester, MN

  4. A Study Using Avelumab in Non-Small Cell Lung Cancer that has Progressed

    Scottsdale/Phoenix, AZ

  5. A Study Using the Esophageal Sponge to Gather Specimens for Management of Dietary Therapy in Eosinophilic Esophagitis

    Rochester, MN

  6. Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

    Rochester, MN

  7. Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors

    Rochester, MN

  8. The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma

    Rochester, MN

  9. Reliability of Various Methods to Test Isometric Strength of Cervical Musculature

    Rochester, MN

  10. A Study Comparing Combination Chemotherapy to Gemcitabine Hydrochloride and Nab-Paclitaxel Given Before Surgery for Treating Patients who have Pancreatic Cancer that can be Removed by Surgery

    Rochester, MN

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