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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1451-1460 of 10627

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  1. Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

    Rochester, MN

  2. Safety of Regional Citrate Anticoagulation Delivered by the Multifiltratepro System in Continuous Renal Replacement Therapy

    Rochester, MN

  3. COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications

    Rochester, MN

  4. Ketamine Associated ACC GABA and Glutamate Change and Depression Remission

    Rochester, MN

  5. SX-682 Treatment in Subjects With Myelodysplastic Syndrome Who Had Disease Progression or Are Intolerant to Prior Therapy

    Jacksonville, FL

  6. The Purpose of This Study is to Compare the Efficacy and Safety of Aficamten (CK-3773274) Compared With Metoprolol Succinate in Adults With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

    Scottsdale/Phoenix, AZ

  7. A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

    Jacksonville, FL, Rochester, MN

  8. A Study of Oral LOXO-305 in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Self-management of Sedative Therapy by Ventilated Patients

    Rochester, MN

  10. A Study to Evaluate Platelet Rich Plasma to Treat Vulvar Lichen Sclerosus

    Jacksonville, FL

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