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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5951-5960 of 11922

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  1. A Study of Student Outcomes from a Fitness and Nutrition Education Program

  2. Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma

    Rochester, MN

  3. Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin

    Rochester, MN

  4. Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients with Early-Stage Breast Cancer that was Removed by Surgery

    Eau Claire, WI

  5. A Study of the Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

    Rochester, MN

  6. Early or Late Foley Removal After Thoracotomy

    Rochester, MN

  7. Spinal Stimulation to Treat Low Back Pain

    Rochester, MN

  8. Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration with Oscillating Expiratory Pressure

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. Observer-blind Study to Evaluate Efficacy, Safety, and Immunogenicity of GSK Biologicals' Herpes Zoster Vaccine GSK1437173A: Unblinding Communication

    Rochester, MN

  10. A Study to Observe Therapy Dog Visits Effects on Nurse Job Satisfaction and Productivity

    Rochester, MN

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