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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A study to assess the safety and efficacy of MANP, a new blood pressure lowering mediation in African Americans with high blood pressure.

    Rochester, MN

  2. Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash

    Rochester, MN

  3. A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

    Scottsdale/Phoenix, AZ

  4. A Study to Determine the Best Individualized Cancer Therapy Using Circulating Tumor DNA (ctDNA) in Patients with GI, CNS, and Thoracic Cancers.

    Jacksonville, FL

  5. Saline-Enhanced Radiofrequency Catheter Ablation for the Treatment of Ventricular Tachycardia

  6. Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil

    Rochester, MN

  7. A Study of Daratumumab in Patients With Relapsed or Refractory Waldenström Macroglobulinemia

    Rochester, MN

  8. Open-Label Extension of CP101 Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects With Recurrence of Clostridium Difficile Infection

    Scottsdale/Phoenix, AZ

  9. A Phase 1 Proof-of-Concept Clinical Trial Evaluating the Safety and Tolerability of Midodrine in Hepatopulmonary Syndrome

    Rochester, MN

  10. A Study to Understand How Feedback from Breathing Muscles Influence Blood Flow and Blood Pressure during Exercise and if this can Reduce a Response in Heart Failure Patients with Breathing Muscle Training

    Rochester, MN

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