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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study of Everolimus with or without Bevacizumab for Treating Patients with Advanced Kidney Cancer that Progressed after First-Line Therapy

  2. A Study of High Dose Nicotine Patch Therapy for Smokeless Tobacco Users

    Rochester, MN

  3. A Study of the Effects of Aliskiren in Patients with Idiopathic Membranous Nephropathy

    Rochester, MN

  4. A Study Screening Mammograms for Women in Their 40s: Mammography Choice

    Rochester, MN

  5. A Study of the Effectiveness of Methotrexate as Initial Treatment and Maintenance of a Steroid Free Remission in Ulcerative Colitis

    Rochester, MN

  6. Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD3)

    Rochester, MN

  7. Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine

    Rochester, MN

  8. A Study of the Safety and Usability of Culture Expanded STEM Cells Derived from the Patient's Own Fat Tissue for Treatment of Knee Osteoarthritis

    Rochester, MN

  9. Real-Time Myocardial Perfusion Echocardiography in the ICU

    Rochester, MN

  10. Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy

    Jacksonville, FL, Rochester, MN

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