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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 4211-4220 of 11316

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  1. A Study to Measure the Effects that Lighting, Sounds, and Temperature in Offices have on the Health of the People Who Work There

    Rochester, MN

  2. A Study Using SAGE-547 for Super Resistant Status Epilepticus

  3. Effect of GS-6615 on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy

    Rochester, MN

  4. A Study of Static versus Articulating Antibiotic Spacer for Periprosthetic Joint Infection in Total Knee Arthroplasty

    Rochester, MN

  5. A Study Comparing the Effectiveness of Tiotropium and Olodaterol in Fixed Dose Combination Over Tiotropium Alone in Reducing Moderate to Severe Wosening of Symptoms in Patients with Severe to Very Severe Chronic Obstructive Pulmonary Disease

    Rochester, MN

  6. A Study Comparing a Vaccine with or without an Autologous Tumor Lysate to Treat Stage III or IV Melanoma to Prevent Recurrence

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. A Study of a Psychotherapeutic Approach Applied to Those Who are Critically Ill to Provide Patients with Psychological Support

    Rochester, MN

  8. Outcomes Associated with Family Member Participation in an Overdose Education and Naloxone Distribution (OEND) Program on the Prevention of Death from Opioid Overdose in a High Risk Population within the Pain Rehabilitation Center (PRC)

    Rochester, MN

  9. A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache

    Scottsdale/Phoenix, AZ

  10. Expanded Access /Compassionate Use Protocol For Relapsed Or Refractory CD33 Positive AML Patients In The USA Without Access To Comparable Or Alternative Therapy

    Rochester, MN

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