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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. The Alliance Patient Questionnaire: A Pilot Study to Determine Questionnaire Feasibility

    Rochester, MN

  2. Exploring Possible Mechanisms that Might Explain Potential Vasodilator and Sensory Effects of TJ-68

    Rochester, MN

  3. A Study for Patients Who Completed VITALITY-ALS (CY 4031) VIGOR-ALS

    Jacksonville, FL

  4. High-Intensity Aerobic Interval Training in Early Outpatient Cardiac Rehabilitation

    Rochester, MN

  5. Teleophthalmology in the Management of Glaucoma

    Rochester, MN

  6. Learning More about How your Brain Works with Decreased Levels of Oxygen

    Rochester, MN

  7. A Study of Upper Limb Function and Movement in Older Patients with Rotator Cuff Tears

    Scottsdale/Phoenix, AZ

  8. AKT Inhibitor MK2206, Combined with Bendamustine Hydrochloride, and Rituximab for Treating Patients who have Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

  9. Mindful Breathing Awareness Through Pursed-Lip Breathing Training

    Rochester, MN

  10. Study of ALN-GO1 in Healthy Adult Subjects and Patients With Primary Hyperoxaluria Type 1

    Rochester, MN

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