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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 85 for transplant

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  • Study status: Open/Status Unknown
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  1. Cardio-Pulmonary Bypass Versus Extracorporeal Membrane Oxygenation as an Independent Risk Factor for Development of Primary Graft Dysfunction Post Lung Transplant

    Jacksonville, FL

  2. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    Rochester, MN

  3. Donor-derived Cell-free DNA Testing in Kidney Transplant Recipients on Reduced Immunosuppression

    Scottsdale/Phoenix, AZ

  4. APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    Scottsdale/Phoenix, AZ

  5. Heart Failure and Cardiothoracic Transplant Biorepository

    Rochester, MN

  6. Acute Respiratory Distress Syndrome (ARDS) and Acute Respiratory Failure (ARF) Following Hematopoietic Stem Cell Transplantation

    Rochester, MN, Scottsdale/Phoenix, AZ

  7. A Study of Kidney Transplant Recipients: Development of a Database for a Multicenter Consortium

    Rochester, MN

  8. The Role of Genetics and Socioeconomic Factors in Outcomes After Kidney Transplantation in Hispanics and American Indians

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study to Compare Urinary Exosomes in Healthy Kidney Donors and Renal Transplant Recipients

    Rochester, MN

  10. A Study to Compare Medical and Non-Medical Coping on Functional Outcomes and Caregiver Burden Among Liver Transplant Patients

    Jacksonville, FL

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