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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 81-90 of 2189 for surgery

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  1. Spatz3 Adjustable Balloon System® (Spatz3) Post Approval Study

    Rochester, MN

  2. A Study to Compare the Outcome of Primary Anatomic Shoulder Arthroplasty Using the Stryker ReUnion System with Implantation of Either a Peg or Keel Glenoid Construction.

    Rochester, MN

  3. A Comparison of Two Ab Interno Procedures in the Treatment of Glaucoma in Patients Undergoing Cataract Extraction

    Jacksonville, FL

  4. A Study to Compare Total Amount of Opioid Use in the First 72 Hours Following Vaginal Hysterectomy Surgery

  5. A Study to Evaluate Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

    Eau Claire, WI, Rochester, MN, La Crosse, WI

  6. A Study to Compare Incisionless Ultrasound Guided Thread Carpal Tunnel Release and Mini Open Carpal in Patients with Bilateral Carpal Tunnel Syndrome

    Rochester, MN

  7. A Study to Evaluate Individualized Prehabilitation for People Undergoing Neo-Adjuvant Radiotherapy and Lower Limb Soft-Tissue Sarcoma Surgery

    Scottsdale/Phoenix, AZ

  8. Dexamethasone in Total Knee Arthroplasty

    Rochester, MN

  9. Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

    Scottsdale/Phoenix, AZ

  10. LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009)

    Rochester, MN

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