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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 871-880 of 2190 for surgery

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  1. CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function Post Anterior Myocardial Infarction - Pilot Study

    Rochester, MN

  2. A Consortium Trial to Evaluate Proton vs. Photon Therapy for Patients with Non-metastatic Breast Cancer

    Jacksonville, FL

  3. A Study of the Effectiveness of Transvaginal Administration of Botulinum-A Toxin for the Treatment of Women with Over Active Bladder (OAB) Syndrome

    Jacksonville, FL

  4. Vaginal Bromocriptine for Treatment of Adenomyosis

    Rochester, MN, Rochester, MN

  5. REDUCE LAP-HF TRIAL II

    Rochester, MN

  6. Early Identification of Chemotherapy Induced Cardiac Toxicity

    Rochester, MN

  7. Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

    Scottsdale/Phoenix, AZ

  8. Predictive Role of Non-Invasive Glucose Assessment During Pregnancy

    Rochester, MN

  9. An Outcomes Study to Assess Statin Residual Risk Reduction with Epanova in High Cardiovascular Risk Patients with Hypertriglyceridemia

  10. Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation

    Rochester, MN

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