A Study Comparing Air versus Blood with Saline as Contrast Shading for Echocardiographic Imaging of the Right Heart and Shunts


About this study

The study aims to answer whether the use of a mixture of blood and saline alone (limited air) provides the same degree of right-heart contrast enhancement as compared to the standard agitated saline (with air), during  echocardiograms.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Will have a clinically indicated transesophageal or transthoracic echocardiogram, as ordered by their physician to detect a shunt

Exclusion Criteria

  • Unwillingness to provide consent to participate in the study

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Garvan Kane, M.D., Ph.D.

Closed for enrollment

More information


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