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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 351-360 of 2028 for surgery

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  1. Vaccine Therapy In Treating Patients With Stage IIIC-IV Ovarian Epithelial, Fallopian Tube, Or Primary Peritoneal Cavity Cancer Following Surgery And Chemotherapy

    Rochester, MN

  2. Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients with Brain Metastases that have been Removed by Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. Observation Or Radiation Therapy In Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed By Surgery

    Rochester, MN

  4. Sapanisertib in Treating Patients With Metastatic or Refractory Pancreatic Neuroendocrine Tumor That Cannot Be Removed by Surgery

    Rochester, MN, Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study In Treating Patients With Kidney Cancer Undergoing Nephrectomy Comparing PERioperative Nivolumab Vs. Observation

    Rochester, MN

  6. Sunitinib Malate with or without Gemcitabine Hydrochloride in Treating Patients with Advanced Kidney Cancer that Cannot be Removed by Surgery

    Rochester, MN

  7. Vaccine Therapy and Resiquimod in Treating Patients with Stage II-IV Melanoma that has been Removed by Surgery

    Rochester, MN

  8. A Study Of Lenvatinib For Treating Patients With Metastatic Or Advanced Pheochromocytoma Or Paraganglioma That Cannot Be Removed By Surgery

    Rochester, MN

  9. Ixabepilone and Temsirolimus in Treating Patients with Solid Tumors that are Metastatic or Cannot ce Removed by Surgery

    Jacksonville, FL, Rochester, MN

  10. Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

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