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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 2028 for surgery

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  1. Cardiac Vascular Reconstruction DynaCT for TAVI Procedures

    Rochester, MN

  2. Mobile Educations Effect on Pain Outcomes

    Rochester, MN

  3. Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

    Eau Claire, WI, Mankato, MN, Rochester, MN, Jacksonville, FL

  4. Ergonomics and Usability of a Head-neck Support Exoskeleton for Plastic Surgery Residents

    Rochester, MN

  5. Study Of AVB-620 In Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  6. Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients with Locally Advanced Rectal Cancer Undergoing Surgery

    Mankato, MN

  7. A Trial Of 15 Fraction Vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy In Patients Requiring Regional Nodal Irradiation

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

    Mankato, MN, Albert Lea, MN, Jacksonville, FL, Rochester, MN

  9. Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

    Scottsdale/Phoenix, AZ

  10. Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy For Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

    Scottsdale/Phoenix, AZ

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