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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1331-1340 of 2193 for surgery

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  1. A Study of Standard Systemic Therapy with or without Definitive Treatment in Treating Participants with Metastatic Prostate Cancer

    La Crosse, WI, Scottsdale/Phoenix, AZ, Rochester, MN

  2. A Study to Evaluate Brain Computer Interface (BCI) and Electrocorticography (ECoG)- based Mapping of Sensori-motor and Language Modalities Utilizing Subdural Electrodes in the Human Brain

    Jacksonville, FL

  3. A Study to Determine the Changes to Visual Fields and Neuropsychological Assessments after Laser Ablation for Epilepsy

  4. A Study of the Bacteria Found in Cancerous and Non-cancerous Breast Tissue

    Rochester, MN

  5. Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients with Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

    Rochester, MN

  6. A Study to Explore if it is Possible to Successfully Obtain Optical Coherence Tomography (OCT) Imaging and Data While Patients Undergo Brain Surgery

    Jacksonville, FL

  7. Observational Study of Wearable Health Monitoring Device

    Rochester, MN

  8. A Study of the Functional Outcome of Tendon Transfers in Brachial Plexus Injuries

    Rochester, MN

  9. MRI Techniques to Treat Seizure Disorders

    Rochester, MN

  10. A Study to Evaluate Outcomes and Complications in Patients that have had Total Shoulder and Reverse Total Shoulder Arthroplasty using Bone Preserving Shoulder Arthroplasty System

    Rochester, MN

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