A Study to Assess Wound Closure Techniques in Primary Spine Surgery Using SPY Intra-operative Angiography


About this study

The purpose of this study is to assess wound perfusion at the site of closure in primary spine surgery between running subcuticular suture, interrupted vertical mattress suture, and staple closure techniques.


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:  

  •  ≥ 18 years old.
  • Primary diagnosis of spinal stenosis.
  • Surgical indication for 1 or 2 level posterior spinal decompression or fusion.

Exclusion Criteria:

  • Previous posterior spinal surgery.
  • Systemic corticosteroid use.
  • Long-term anticoagulation treatment.
  • Diagnosis of diabetes mellitus.
  • Diagnosis of peripheral arterial disease.
  • Current smoker.
  • Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Arjun Sebastian, M.D.

Open for enrollment

Contact information:

Kelsey Klapperick

(507) 293-7392


More information


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