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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1151-1160 of 2190 for surgery

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  1. Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

    Rochester, MN

  2. A Study to Assess Respiratory Muscle Training as a Quality Improvement of Perioperative Care in LVAD Patients

    Rochester, MN

  3. Posterior Fossa Decompression with or without Duraplasty for Chiari Type I Malformation with Syringomyelia

    Rochester, MN

  4. A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor

    Scottsdale/Phoenix, AZ

  5. A Study to Reduce Cardiomyopathy in Breast Cancer Patients Being Treated With Trastuzumab

    Rochester, MN

  6. Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults

    La Crosse, WI, Rochester, MN

  7. A Study to Evaluate the Effectiveness and Safety of Ralinepag To Improve Treatment Outcomes in Peripheral Arterial Hypertension (PAH) Patients

    Scottsdale/Phoenix, AZ

  8. LS1681: A Study of AR160 in Treating Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

    Rochester, MN

  9. A Study Evaluating the Efficacy and Safety of Botulinum Toxin Type A and Solifenacin in Patients with Overactive Bladder and Urinary Incontinence

  10. A Study to Determine if Early Changes of Pulmonary Artery Hypertension can be Seen by Adding Exercise During Cardiac Magnetic Resonance Imaging (MRI)

    Jacksonville, FL

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