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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 91-100 of 108 for spine

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  1. Shoulder Kinematics and Loading during Activities of Daily Living and Ambulation in Subjects with Spinal Cord Injury

    Rochester, MN

  2. A Study to Collect Clinical Outcomes Data of Patients Treated with the Rampart Duo Device for Lateral Lumbar Interbody Fusion Procedure Performed at One or Two Contiguous Levels

    Rochester, MN

  3. Primary Tumor Research and Outcome Network (PTRON) Registry

    Rochester, MN

  4. A Study to Gather Genetic information for Further Study from Patients with Idiopathic Scoliosis and Their Families

    Rochester, MN

  5. Cerebral Spinal Fluid Evaluation in Individuals Who Have Idiopathic Normal Pressure Hydrocephalus (INPH)

    Rochester, MN

  6. A Study of Treatment of Painful Spinal Implants using Fluoroscopically Guided Injections

    Rochester, MN

  7. A Study to Evaluate the Blood Test Thromboelastogram (TEG) to Manage Patients Undergoing Multi-level Spinal Fusion Surgery

    Scottsdale/Phoenix, AZ

  8. A Study to Establish An Adolescent Idiopathic Scoliosis Outcomes Database Registry

    Rochester, MN

  9. Mayo Clinic Spinal Cord Injury (SCI) Rehabilitation Research Registry

    Rochester, MN

  10. A Study to Determine the Effectiveness of Spinal Cord Stimulation for the Treatment of Refractory Angina Pectoris

    Rochester, MN

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