A Study Of Secondary Medical Complications

Overview

About this study

The purpose of this study is to track the chronological history in autonomic recovery over the first 12 months following acute SCI.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 18-75 years old

  • Spinal cord injury with neurological level of injury from C6-T12, ASIA Impairment Scale A-D.50 Either acute SCI <3 months prior (n=10) or chronic SCI (>1 year since injury, n=8).

 

Exclusion Criteria:

  • Symptoms of cardiovascular (including, but not limited to: hypertension, stroke, chest pain, etc.), respiratory, peripheral neurological or autonomic disease (particularly diabetes mellitus requiring treatment)

  • Women who are pregnant or lactating

  • Taking or being administered a medication known to potentially have adverse interactions with phenylephrine

  • In the judgement of the principal investigator, any illness or condition that will interfere with the patient’s ability to comply with the protocol, compromise patient safety, or interfere with the interpretation of the study results.

 Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

 

Eligibility last updated 05/16/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Ryan Solinsky, M.D.

Open for enrollment

Contact information:

Zachary Pohlkamp

(507) 422-0140

pohlkamp.zachary@mayo.edu

More information

Publications

Publications are currently not available
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CLS-20595403

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