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Rochester, MN
Describes the nature of a clinical study. Types include:
This is a 3-day study comparing pyridostigmine versus placebo in the treatment of postural tachycardia syndrome (POTS). The researchers expect pyridostigmine to improve tachycardia and stabilize blood pressure.
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Open for enrollment
The purpose of this study is to examine the efficacy of a novel exercise prescription methodology of high-intensity interval training (HIIT), compared to low/moderate intensity continuous training (L/MICT), to maximize improvement in overall exercise capacity and exertional symptoms through improvement in cardiac output via stroke volume. We hypothesize that patients enrolled in HIIT will demonstrate greater improvement in peak exercise capacity and symptom dependent quality of life compared to patients enrolled in L/MICT.
The purposes of this study are to compare the functional connectivity in adolescent patients with Postural Orthostatic Tachycardia Syndrome (POTS) both with and without chronic pain, to those with chronic pain alone, to that of healthy controls; to evaluate whether there is a change in functional connectivity following participation in an intensive rehabilitation-oriented program previously demonstrated to have excellent outcomes with regard to functional recovery and symptom control; and to correlate outcomes using standardized symptom and function rating scales to imaging findings.