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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 25 for mesothelioma

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  1. Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma

    Rochester, MN

  2. Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma

    Scottsdale/Phoenix, AZ

  3. Intrapleural Measles Virus Therapy in Patients with Malignant Pleural Mesothelioma

    Rochester, MN

  4. Placebo Controlled Study of VS-6063 in Subjects with Malignant Pleural Mesothelioma

    Rochester, MN

  5. A Study in Subjects with Malignant Pleural Mesothelioma to Assess ADI-PEG 20 with Pemetrexed and Cisplatin

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  6. A Study of the Safety and Effectiveness of Amatuximab in Combination with Pemetrexed and Cisplatin in Subjects with Unremoveable Malignant Pleural Mesothelioma

    Rochester, MN

  7. Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

    Rochester, MN

  8. Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study of Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma

    Rochester, MN

  10. A Study to Evaluate the Effectiveness and Safety of rAd-IFN Administered With Celecoxib and Gemcitabine in Patients With Malignant Pleural Mesothelioma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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