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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 147 for kidney and hypertension

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  1. AKI Prevention and Early Intervention in Patients Undergoing VAD Placement

    Rochester, MN

  2. Open-Label Tolvaptan Study in Subjects With ADPKD

    Rochester, MN

  3. A Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

    Rochester, MN

  4. Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)

    Jacksonville, FL

  5. A Study to Understand Serum Biotin Clearance as a Means to Mitigate the Risk of Biotin Interference with Clinical Laboratory Tests

    Rochester, MN

  6. Role Of Phosphorus And FGF 23 In Patients With Dent Disease

    Rochester, MN

  7. Terlipressin for HRS-AKI in Liver Transplant Candidates (INFUSE) (INFUSE)

    Rochester, MN

  8. Lenalidomide and Low-Dose Dexamethasone in Patients with Previously Treated Multiple Myeloma and Kidney Dysfunction

  9. Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy in Patients With High-Grade Upper Tract Urothelial Carcinoma

  10. Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery

    Rochester, MN

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