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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 271-280 of 981 for hematology

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  1. Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia

    Rochester, MN

  2. Trial of Eltrombopag During Consolidation Therapy in Adults With AML in Complete Remission

    Rochester, MN

  3. Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients with Locally Advanced Rectal Cancer Undergoing Surgery

    Mankato, MN

  4. Study Comparing CB-839 with Cabozantinib vs. Cabozantinib with Placebo in Patients with Metastatic Renal Cell Carcinoma

  5. Focal Laser Ablation of Prostate Cancer Tumors

    Rochester, MN

  6. Tucatinib and Trastuzumab for Patients with HER2-positive Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Study of SC-003 in Subjects With Platinum-Resistant/Refractory Ovarian Cancer

    Rochester, MN

  8. A Study Comparing Scrambler Therapy versus TENS Therapy in Treating Patients with Chemotherapy-Induced Peripheral Neuropathy

    Rochester, MN

  9. Novel Support Options in Autologous Stem Cell Transplant for Multiple Myeloma

    Scottsdale/Phoenix, AZ

  10. First-in-Human Study of FLX925 in Subjects with Relapsed or Refractory Acute Myeloid Leukemia

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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