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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 314 for heart disease

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  1. A Study to Compare the Effectiveness of an Invasive Treatment Approach versus Conservative Medication Alone Strategy for Patients with Stable Ischemic Heart Disease

    Jacksonville, FL

  2. Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk. (CalmiGo)

    Rochester, MN

  3. Cardiovascular Health Promotion Among African-Americans by FAITH!

    Rochester, MN

  4. A Study of Stress Management Intervention in a Women's Heart Clinic, The Heart SMART Program

    Rochester, MN

  5. A Study to Determine the Impact of Individualized Estrogen Therapy on Cardiovascular Disease Risk Parameters in Young Women after Bilateral Oophorectomy

    Rochester, MN

  6. Reducing CVD Risk in African Americans Faith Communities

    Rochester, MN

  7. A Study to Improve Cardiovascular Health Among African Americans within Faith Communities

    Rochester, MN

  8. A Study to Compare the Effectiveness of Invasive versus Conservative Medical Approaches in Patients with Stable Ischemic Heart Disease and Advanced Chronic Kidney Disease

    Scottsdale/Phoenix, AZ

  9. Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)

    Jacksonville, FL

  10. A Study to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair with the HARPOON™ System

    Rochester, MN

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