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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 71 for cerebrovascular

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  1. Massage Technique for Pain, Anxiety and Delirium in SAH Patients

    Rochester, MN

  2. SDM for Stroke Prevention in Atrial Fibrillation

    Rochester, MN

  3. PROTECTED TAVR: Stroke PROTECTion With SEntinel During Transcatheter Aortic Valve Replacement

    Rochester, MN

  4. A Study to Compare Non-invasive Near-infrared Spectroscopy (NIRS) to Invasive Licox Intracranial Pressure Monitoring in Neurocritical Care

    Rochester, MN

  5. AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

    Rochester, MN

  6. ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial

    Rochester, MN

  7. Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Stroke Care

    Jacksonville, FL

  8. Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Atrial Fibrillation

    Rochester, MN

  9. A Study of Computer Simulation of Endovascular Repair of Cerebral Aneurysms Aneurysms

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study of Clopidogrel for the Prevention of TIA and Minor Ischemic Stroke

    Scottsdale/Phoenix, AZ

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