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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 71 for cerebrovascular

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  1. Detection of Vascular and Inflammatory Plasma Biomarkers in Patients Diagnosed with Obstructive Sleep Apnea and MRI-defined Cerebral Small Vessel Disease

    Jacksonville, FL

  2. Study to Determine Eligibility for Lung Cancer Screening in Patients with Acute or Prior Cerebrovascular Accident (CVA)

    Jacksonville, FL

  3. A Study to Evaluate Cerebrovascular Reserve in Steno-Occlusive Disease Using the RespirAct Device

    Rochester, MN

  4. A Study of Empathy in Stroke Telemedicine

    Jacksonville, FL

  5. A Study to Improve Patient Access to Stroke Therapy

    Eau Claire, WI

  6. A Study of the Clinical Presentation and Natural History of Vertebrobasilar Non-Saccular and Dolichoectatic (Types of Symptom and Brain Location) Aneurysms

    Rochester, MN

  7. Computer Vision-based Assessment of Upper Extremity Motor Function in Stroke Patients

    Scottsdale/Phoenix, AZ

  8. A Study to Collect Health Related Data and Biological Samples that will Enable Researchers to Understand the Cause of Cryptogenic New-onset Refractory Status Epilepticus

    Rochester, MN

  9. Prolonged Cardiac Monitoring in Individuals with High Risk for Atrial Fibrillation and Stroke

    Jacksonville, FL

  10. A Multimodal Monitoring (MMM) Computer to Detect Physiologic Trends in Data in Neurointensive Care Unit Patients

    Jacksonville, FL, Rochester, MN

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