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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 507 for center for individualized medicine

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  1. A Study to Evaluate the Usability of a Web-based Software Application for the Writing of Electronic Health Records-driven Phentyping Algorithms (Complicated System of Inclusion and Exclusion Criteria to Place Patients into Groups)

  2. Pediatric MSC-AFP Sub-study for Crohn's Fistula

    Rochester, MN

  3. A Study of a Stem Cell Fistula Plug to Treat Cryptoglandular Perianal Fistulas

    Rochester, MN

  4. Phase 1 Crohn's Pediatric Sub-study of MSC AFP

    Rochester, MN

  5. Senescence in Chronic Kidney Disease

    Rochester, MN

  6. Study Evaluating the Side Effects of Bone Marrow-Derived Stem Cells When Injected Into the Facet Joints for the Treatment of Painful Arthropathies

    Jacksonville, FL

  7. Re-treatment From a Phase I Study of MSC-AFP in Patients With Perianal Fistulas

    Rochester, MN

  8. A Study to Evaluate the Addition of Immunotherapy into Adjuvant Therapy for Non-small Cell Lung Cancer

    Rochester, MN

  9. A Study to Evaluate Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis

    Rochester, MN

  10. A Study of the Safety and Effectiveness of Stem Cell Fistula Plugs to Repair Post Surgical Leak Fistulas

    Rochester, MN

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