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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 931-940 of 2867 for cancer

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  1. MUC1 TCell receptor repertoire

    Rochester, MN

  2. A Novel Vaccine (EO2463) As Monotherapy And In Combination, For Treatment Of Patients With Indolent Non-Hodgkin Lymphoma

    Rochester, MN

  3. Isotretinoin With or Without Monoclonal Antibody Ch14.18, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma

    Rochester, MN

  4. Testing An Active Form Of Tamoxifen (4-hydroxytamoxifen) Delivered Through The Breast Skin To Control Ductal Carcinoma In Situ (DCIS) Of The Breast

  5. A Study To Evaluate Pembrolizumab For Surgically Treated Adjuvant Merkel Cell Carcinoma

    Eau Claire, WI, Rochester, MN

  6. A Study Of Safety, Tolerability, Pharmacokinetic And Pharmacodynamics (PK/PD) In Patients With Hematologic Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study Of ONC201 For Patients With H3 K27M-mutant And/or Midline High Grade Gliomas

    Jacksonville, FL, Rochester, MN

  8. A Study To Evaluate Radiotherapy To The Whole Breast Or Post-mastectomy Chest Wall Including Regional Nodal Irradiation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study Of The Drugs Selumetinib Vs. Carboplatin And Vincristine In Patients With Low-Grade Glioma

    Rochester, MN

  10. Polyphenon E in Treating Patients with High-Risk of Colorectal Cancer

    Rochester, MN

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