Clinical Trials

Treating Breast Cancer Patients Undergoing Trastuzumab Treatment with Carvedilol to Reduce Incidence of Heart Failure

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  3 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  1 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Hypofractionated Radiation Therapy in Treating Participants With Prostate Cancer High-Risk Features Following Radical Prostatectomy

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  3 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

A Study of Pembrolizumab and Ruxolitinib Phosphate for Treating Patients with Metastatic Stage IV Triple Negative Breast Cancer

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  1 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

• Study type:

  Interventional Show What is this?

  Describes the nature of a clinical study. Types include:

   

  • Observational study — observes people and measures outcomes without affecting results.
  • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
  • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

• Study phase:

  2 Show What is this?
  During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.