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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 301-310 of 2932 for cancer

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  1. Vaccine Therapy in Treating Patients With Previously Treated Stage II-III HER2-Positive Breast Cancer

    Rochester, MN

  2. Cognitive Training For Cancer Related Cognitive Impairment In Breast Cancer Survivors

    Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  3. Water Vapor Ablation For Localized Intermediate Risk Prostate Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. A Study to Evaluate the Effects of Exercise on Fatigue in Thyroid Cancer Survivors

    Rochester, MN

  5. I-SPY 2 TRIAL: Neoadjuvant And Personalized Adaptive Novel Agents To Treat Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. Evaluation Of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib In Locally Advanced Or Metastatic ER+/HER2- Breast Cancer With An ESR1 Mutation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Atezolizumab In Combination With A Multi-Kinase Inhibitor For The Treatment Of Unresectable, Locally Advanced, Or Metastatic Liver Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. Team Based Psychosocial Care to Promote, Maintain and Restore Wellness of Breast Cancer Patients

  9. Study Of Targeted Therapy Vs. Chemotherapy In Patients With Thyroid Cancer

    Jacksonville, FL, Rochester, MN

  10. A Study To Evaluate Adjuvant Ado-Trastuzumab Emtansine (T-DM1) In HER2 Positive Breast Cancer

    Rochester, MN

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