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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 2061-2070 of 3416 for cancer

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  1. Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma

  2. Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

    Rochester, MN, Jacksonville, FL

  3. Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates

    Scottsdale/Phoenix, AZ

  4. High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. DN24-02 as Adjuvant Therapy in Subjects with High Risk HER2+ Urothelial Carcinoma

  6. A Study to Evaluate Changes to the Design of an Improved Mammography Imaging Table

  7. Proton or Photon RT for Retroperitoneal Sarcomas

    Rochester, MN

  8. A Study to Evaluate Ruxolitinib for the Treatment of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplant

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate the Safety and Effectiveness of the Augmented Endoscopy System for Mucosal Lesion Detection During Colonoscopy for Colon Rectal Cancer.

    Scottsdale/Phoenix, AZ, Jacksonville, FL, La Crosse, WI, Eau Claire, WI

  10. Cisplatin, Intensity-Modulated Radiation Therapy, and Pembrolizumab in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma

    Rochester, MN

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