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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1881-1890 of 2787 for cancer

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  1. A Study of the Effectiveness and Safety of CTL019 in Adult Patients with Diffuse Large B-Cell Lymphoma

  2. Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers

    Rochester, MN

  3. The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis

    Jacksonville, FL, Rochester, MN

  4. A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase

    Rochester, MN

  5. Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps

    Rochester, MN

  6. Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors

    Rochester, MN

  7. Endoscopic Ultrasound Guided Fine Needle Biopsy (EUS-FNB-SC) Using a Novel Fork Needle

    Jacksonville, FL

  8. Panchromoendoscopy using Oral Indigo Carmine Mixed with Polyethylene Glycol Prep

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate S-Adenosyl-L-Methionine for the Treatment of Hot Flashes

    Rochester, MN

  10. A Study to Evaluate the Effectiveness and Safety of Relacorilant

    Rochester, MN

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