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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1551-1560 of 3398 for cancer

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  1. A Dose Escalation Study Of HFB301001 In Adult Patients With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

  3. Smoking Cessation Prior to Surgery to Reduce Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes

    Mankato, MN

  4. A Safety Study of SGN-CD19A for Leukemia and Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  5. Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study To Evaluate Treatment Of Established Chemotherapy-induced Neuropathy With Fingolimod

    Mankato, MN, Rochester, MN

  7. Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

    Rochester, MN

  8. Quantitative Transmission Imaging Compared With MRI As Supplemental Screening For High Lifetime Risk Of Breast Cancer

    Rochester, MN

  9. A Study of Proton Radiation Divided into Fewer Doses for Low Risk Prostate Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. Doxorubicin Hydrochloride, Vinblastine, Dacarbazine, Brentuximab Vedotin, And Nivolumab In Treating Patients With Stage I-II Hodgkin Lymphoma

    Rochester, MN

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