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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1261-1270 of 2933 for cancer

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  1. A Study Using Clofarabine and Cytarabine in Treating Children with Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

  2. Inotuzumab Ozogamicin In Treating Younger Patients With Relapsed Or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

    Rochester, MN

  3. Brentuximab Vedotin And Nivolumab With Or Without Ipilimumab In Treating Patients With Relapsed Or Refractory Hodgkin Lymphoma

    Rochester, MN

  4. A Study Of Heated Intra-peritoneal Chemotherapy (H.I.P.E.C.) With Doxorubicin And Cisplatin In Pediatric Patients With Pelvic And Abdominal Rhabdomyosarcoma

    Rochester, MN

  5. A Study Of APG-2575 Alone Or In Combination With Other Therapeutic Agents To Treat Relapsed And/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

    Jacksonville, FL

  6. Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye

    Rochester, MN

  7. Study Of Tirabrutinib (ONO-4059) In Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Phase 1/2 Dose Escalation And Efficacy Study Of Anti-CD38 Monoclonal Antibody In Patients With Selected CD38+ Hematological Malignancies

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. A Study To Develop And Validate Hybrid Molecular Imaging To Transform The Care Of Hepatocellular Carcinoma Patients

    Rochester, MN

  10. Study Of AZD0466 Monotherapy Or In Combination In Patients With Advanced Haematological Malignancies

    Jacksonville, FL

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