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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1241-1250 of 3418 for cancer

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  1. A Trial of TTI-621 for Patients With Hematologic Malignancies and Selected Solid Tumors

    Rochester, MN, Jacksonville, FL

  2. A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Isatuximab in Patients With Multiple Myeloma

    Scottsdale/Phoenix, AZ

  3. A Study to Evaluate the Effectiveness and Safety of Cobomarsen (MRG-106) in Subjects with Mycosis Fungoides Who Have Completed the SOLAR Study

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

    Eau Claire, WI, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN, La Crosse, WI

  5. CBT-1® in Combination With Doxorubicin in Patients With Metastatic, Unresectable Sarcomas Who Previously Progressed on Doxorubicin

    Jacksonville, FL

  6. A Study Of CTX-712 In Relapsed/Refractory Acute Myeloid Leukemia And Higher Risk Myelodysplastic Syndromes

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of the Perceptions About Colon Cancer of Upper Midwest Native Americans and Their Health Care Providers

  8. A pivotal study of derazantinib in patients with inoperable or advanced intrahepatic cholangiocarcinoma and FGFR2 gene fusions or FGFR2 gene mutations or amplifications

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study to Evaluate the Effectiveness and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

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