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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 420 for breast cancer

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  1. Comparison of Combination Chemotherapy Regimens in Treating Older Women Who Have Undergone Surgery for Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Single Arm Pilot Trial Of Adaptive Therapy (AT) With Capecitabine For The Treatment Of Breast Cancer

    Scottsdale/Phoenix, AZ

  3. A Study To Evaluate Decreasing Chemotherapy For Breast Cancer Patients After Pre-surgery Chemo And Targeted Therapy

    Eau Claire, WI, La Crosse, WI, Rochester, MN

  4. A Study To Evaluate Lasofoxifene Versus Fulvestrant In Advanced Or Metastatic ER+/HER2− Breast Cancer Patients With An ESR1 Mutation

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study To Evaluate Regional Radiotherapy In Biomarker Low-Risk Node Positive Breast Cancer

    Jacksonville, FL

  6. Doxorubicin Hydrochloride, Cyclophosphamide, And Paclitaxel With Or Without Bevacizumab In Treating Patients With Lymph Node-Positive Or High-Risk, Lymph Node-Negative Breast Cancer

    La Crosse, WI

  7. Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

  8. Eliminating Breast Cancer Surgery In Exceptional Responders With Neoadjuvant Systemic Therapy

    Rochester, MN

  9. A Study Of Hypofractionated Radiotherapy To The Whole Breast Alone Before Breast Conserving Surgery

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. Pre-op Pembro + Radiation Therapy In Breast Cancer (P-RAD)

    Rochester, MN

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