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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 73 for alzheimer's

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  1. Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo

    Jacksonville, FL

  2. A Long Term Study of Molecular and Structural Imaging in Atypical Alzheimer's Disease

    Rochester, MN

  3. Exercise in Asymptomatic Pre-Alzheimer's Disease Pilot Study

    Jacksonville, FL

  4. A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

    Jacksonville, FL

  5. 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease

    Jacksonville, FL

  6. An Extension Study of ABBV-8E12 in Early Alzheimer's Disease (AD)

    Jacksonville, FL

  7. An Efficacy and Safety Trial of MK-8931 in Mild to Moderate Alzheimer's Disease (P07738)

    Scottsdale/Phoenix, AZ

  8. A Study of the Effectiveness of LY3314814 in Patients with Mild Alzheimer's Disease Dementia

    Jacksonville, FL

  9. A Study to Evaluate Compensatory Training to Support Everyday Function and Adherence to Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease

    Scottsdale/Phoenix, AZ

  10. A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

    Scottsdale/Phoenix, AZ

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