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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 104 for alzheimer's

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  1. A Study to Evaluate Caregiver Connections via Technology for Patients with Alzheimer's and Other Types of Dementia

    Rochester, MN

  2. A Safety, Methodological and Exploratory Biomarkers Study to Slow Disease Progression

    Jacksonville, FL

  3. AHEAD 3-45 Study

    Rochester, MN, Jacksonville, FL

  4. Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline

    Scottsdale/Phoenix, AZ

  5. Metabolic Cerebral Imaging in Incipient Dementia (MCI-ID)

  6. Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI and AD Subjects

    Scottsdale/Phoenix, AZ

  7. Bridging Study of C11 PiB and F18 Flutemetamol Brain PET

    Rochester, MN

  8. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  9. DaTSCAN Imaging in Aging and Neurodegenerative Disease

    Rochester, MN, Jacksonville, FL

  10. A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

    Rochester, MN

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