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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 28 for Spinal cord injury

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  1. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia

    Rochester, MN

  2. Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect)

    Rochester, MN

  3. A Study to Compare HF10 Therapy Combined With CMM to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain

    Scottsdale/Phoenix, AZ

  4. A Study to Compare HF10 Therapy Combined with Conventional Medical Management (CMM) to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain

    Rochester, MN

  5. Spinal Stimulation to Treat Low Back Pain

    Rochester, MN

  6. Effects of Music-Assisted-Relaxation on Anxiety and Pain for Patients with Spinal-Cord Injury

    Rochester, MN

  7. A Study of Health and Mobility Benefits Resulting from the Use of an Exoskeleton in Individuals with a Spinal Cord Injury

    Rochester, MN

  8. Spinal Cord Injury Rehabilitation Research Registry

    Rochester, MN

  9. Analysis of Spinal Cord Stimulation Usage Over a 15-Year Period

    Scottsdale/Phoenix, AZ, Rochester, MN

  10. A Study to Survey Epidural User Experience for Individuals with Spinal Cord Injury Paralysis

    Rochester, MN

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