A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia


About this study

The purpose of this study is to produce preliminary data testing the feasibility and effectiveness of high intensity interval training (HIIT) on cardiovascular health parameters in individuals with paraplegia.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Spinal cord injury located at or below the seventh thoracic vertebrae.
  • Manual wheelchair user (primary means of mobility)At least 6 months post-SCI.
  • At least 18 years of age.
  • Able to perform a high-intensity exercise program.
  • Willingness to participate in 16 weeks of an exercise program.

Exclusion Criteria:

  • Spinal cord injury at or above the sixth thoracic vertebrae.
  • Manual wheelchair is not the primary means of mobility (e.g., community ambulators, power wheelchair users).
  • Any documented or reported health condition that would be contraindicated to a progressive exercise program (active upper limb musculoskeletal injuries, autonomic instability, unstable cardiopulmonary disease such as unstable angina, COPD, etc., or pregnancy).
  • Any illness or condition which, based on the research team’s assessment, will compromise with the patient’s ability to comply with the protocol, patient safety, or the validity of the data collected during this study.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kristin Garlanger, D.O.

Closed for enrollment

Contact information:

Tyson Scrabeck CCRP



More information


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