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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 315 for Lung cancer

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  1. Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy

    Rochester, MN

  2. University of California Minority Patient-Derived Xenograft (PDX) Development and Trial Center (UCaMP) to Reduce Cancer Health Disparities

    Jacksonville, FL

  3. Therapeutic Drug Monitoring of Pembrolizumab and Nivolumab to Determine Dosages for Cancer Treatment

    Rochester, MN

  4. A Study to Isolate and Test Circulating Tumor Cells Using the ClearCell® FX EP+ System

    Rochester, MN

  5. A Study of Performing Surgery for Resectable Malignant Pleural Mesothelioma After Radiation Therapy

    Rochester, MN

  6. Biomarkers to Predict for and Monitor Response to PD-1/PD-L1 Inhibitors

    Rochester, MN, Jacksonville, FL

  7. A Study to Evaluate Hormone Concentrations in Patients with Metastatic Cancer

    Rochester, MN

  8. A Study to Explore the Effects of the Measles Virus on Tumor Immunity

    Rochester, MN

  9. Assessment of the Mechanical Properties of Lung Parenchyma using Magnetic Resonance Elastography in Lung Cancer

    Rochester, MN

  10. Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

    Scottsdale/Phoenix, AZ

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