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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 914 for Cancer

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  1. A Study to Compare Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors

    Rochester, MN

  2. A Global, Randomized, Placebo-controlled Phase 3 Study of Fruquintinib in Patients with Refractory Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial 

    Rochester, MN

  4. A Study to Evaluate MEN1611 and Cetuximab in Mutated, Metastatic Colorectal Cancer Patients

    Scottsdale/Phoenix, AZ

  5. A Study to Evaluate A Resilient Living Program for Patients with Advancer Cancer and Their Caregivers

    Rochester, MN

  6. A Study to Evaluate Tepotinib Combined with Cetuximab to Treat Left-Sided Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  7. Pembrolizumab in Treating Patients With Locally Advanced Bladder Cancer

    Eau Claire, WI, Scottsdale/Phoenix, AZ, La Crosse, WI

  8. A Study to Evaluate Whether Probiotics for Gut Microbiome Will Target Cancer Immune Microenvironment in Breast and Lung Cancer

    Jacksonville, FL

  9. A Trial of ZL-1201 in Subjects with Advanced Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  10. VSV-hIFNbeta-NIS in Treating Patients With Stage IV or Recurrent Endometrial Cancer

    Rochester, MN

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