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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 928 for Cancer

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  1. A Study to Evaluate Neoadjuvant and Personalized Agents to Treat Breast Cancer

    Rochester, MN

  2. A Study to Compare Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors

    Rochester, MN

  3. A Study to Evaluate A Resilient Living Program for Patients with Advancer Cancer and Their Caregivers

    Rochester, MN

  4. A Study to Evaluate the Effectiveness and Safety of Fruquintinib (HMPL-013) in Patients With Metastatic Colorectal Cancer (FRESCO-2)

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  5. Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial 

    Rochester, MN

  6. A Study to Evaluate MEN1611 and Cetuximab in Mutated, Metastatic Colorectal Cancer Patients

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate Tepotinib Combined with Cetuximab to Treat Left-Sided Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. Pembrolizumab in Treating Patients With Locally Advanced Bladder Cancer

    Eau Claire, WI, Scottsdale/Phoenix, AZ, La Crosse, WI

  9. A Study of TAS-120 in Patients With Metastatic Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  10. A Trial of ZL-1201 in Subjects with Advanced Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

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