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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 821 for Cancer

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  1. A Study to Compare Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors

    Rochester, MN

  2. A Study to Evaluate Non-Operative Management and Early Response Assessment in Rectal Cancer

    Rochester, MN

  3. Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

    Albert Lea, MN, Eau Claire, WI, Rochester, MN

  4. Study of Oral LOXO-338 in Patients With Advanced Blood Cancers

    Jacksonville, FL, Rochester, MN

  5. Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Advanced Cancer Patients

    Rochester, MN, Mankato, MN

  6. A Study Evaluating the Safety and Effectiveness of Therapies in Patients with Metastatic Colorectal Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Rose Geranium in Sesame Oil Nasal Spray for the Improvement of Nasal Vestibulitis Symptoms in Cancer Patients Receiving Chemotherapy

    Albert Lea, MN, Mankato, MN, Rochester, MN

  8. Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial 

    Rochester, MN

  9. A Study to Evaluate Whether Probiotics for Gut Microbiome Will Target Cancer Immune Microenvironment in Breast and Lung Cancer

    Jacksonville, FL

  10. ALPN-202 With PD-1 Inhibition in Advanced Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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