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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 32 for Anesthesiology and Perioperative Medicine

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  • Study status: Open/Status Unknown
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  1. Learning More about How your Brain Works with Decreased Levels of Oxygen

    Rochester, MN

  2. A Study to Analyze the Amount of Antibiotic Absorbed into Tissues Comparing Two Different Modes of Administration

    Scottsdale/Phoenix, AZ

  3. Study to Evaluate the Effects of Vitamin B3 Derivative on Bone, Skeletal, Muscle and Metabolic Functions in Aging

    Rochester, MN

  4. Exparel Injection for Postoperative Orbital Pain

    Rochester, MN

  5. A Study to Evaluate Ultrasound-guided Erector Spinae Plane Blocks

    Rochester, MN

  6. A Study to Analyze the Effects of Exparel for Post-Surgery Pain Control in Patients Undergoing Penile Prosthesis Placement

    Rochester, MN

  7. A Study to Evaluate the Central Mechanisms of Sympathetic Neural Discharge

    Rochester, MN

  8. Tobacco Dependence Intervention Knowledge, Practices, and Attitudes among Registered Nurses

    Rochester, MN

  9. A Study of Oxygen Binding to Hemoglobin During Exercise and Hypoxia in Humans.

    Rochester, MN

  10. A Study to Evaluate AAV8-human Cocaine Hydrolase to Treat Cocaine Use Disorder

    Rochester, MN

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