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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 12 for

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  1. Hydroxocobalamin as a New and Possibly Superior Treatment for Refractory Vasoplegic Syndrome during Liver Transplant Surgery

    Jacksonville, FL

  2. Treating Adult Patients with Primary Sclerosing Cholangitis with Oral Vancomycin in a Randomized Trial

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

    Rochester, MN

  4. A Study to Develop a Breath Analysis Test

    Jacksonville, FL

  5. Tissue and Blood Registry for Individuals with Liver and Biliary Tumors

    Jacksonville, FL

  6. A Study to Better Understand Why Patients Gain Weight After Undergoing Liver Transplantation

    Rochester, MN

  7. A Study to Evaluate Cardiopulmonary Exercise Testing in Liver Transplant Candidates

    Scottsdale/Phoenix, AZ

  8. A Study Looking at the Impact of Gabriel House of Care (a Hospital Hospitality House, HHH) on the Quality of Life and Mood of Liver Transplant Patients

    Jacksonville, FL

  9. A Pilot Study Examining Thiamine Deficiency in Patients Admitted to the Hospital for Liver Transplantation

    Jacksonville, FL

  10. Lost Wages Support for Living Organ Donors Demonstration Project

    Rochester, MN, Scottsdale/Phoenix, AZ

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