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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 27 for Neurosurgery

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  • Study status: Open/Status Unknown
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  1. Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

    Rochester, MN

  2. A Study to Evaluate fMRI of Active Deep Brain Stimulation in Epilepsy

    Jacksonville, FL

  3. A Study to Compare HF10 Therapy Combined With CMM to CMM Alone in the Treatment of Non-Surgical Refractory Back Pain

    Scottsdale/Phoenix, AZ

  4. A Study to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection Using Intraoperative Brain Microdialysis

    Rochester, MN

  5. ENRICH: Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH) (ENRICH)

    Jacksonville, FL

  6. Treatment of Brain AVMs (TOBAS) Study

    Jacksonville, FL

  7. A Study to Establish a Registry of Deep Brain Stimulation with the VERCISE™ System

    Jacksonville, FL

  8. Acupuncture For The Treatment of Autonomic Dysfunction

    Jacksonville, FL

  9. A Study to Evaluate the Feasibility of Intraoperative Microdialysis (tissue sampling) during Neurosurgery for Central Nervous System Malignancies

    Rochester, MN

  10. Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN

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