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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-9 of 9 for Addiction Services

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  1. A Study to Evaluate AAV8-human Cocaine Hydrolase to Treat Cocaine Use Disorder

    Rochester, MN

  2. A Study to Evaluate the Safety of Acamprosate for Alcohol Use Disorder

    Rochester, MN, Mankato, MN

  3. A Study to Evaluate the Safety, Tolerability and Effectiveness of V117957 in Subjects with Insomnia Associated with Alcohol Cessation

    Rochester, MN

  4. A Study to Evaluate Smartphone-based Digital Phenotyping for Relapse Prediction in Alcohol-associated Liver Disease

    Rochester, MN

  5. A Study to Analyze the Effects of Buprenorphine on Hyperalgesia in Patients with Opioid Use Disorder

    Rochester, MN

  6. Acamprosate Treatment Outcome

    Rochester, MN, Albert Lea, MN

  7. A Study to Evaluate Treatment of Delayed Sleep-Wake Phase Syndrome with Melatonin in Patients with Comorbid Alcohol Use Disorders

    Rochester, MN

  8. Attitudes and Beliefs About Gene Transfer Therapy in Adults with Cocaine Use Disorder

    Rochester, MN

  9. A Study to Analyse the Genetic Makeup of Those with Opioid and Substance Use Disorders

    Albert Lea, MN, Rochester, MN

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