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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 34 for Anesthesiology and Perioperative Medicine

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  • Study status: Open/Status Unknown
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  1. Learning More about How your Brain Works with Decreased Levels of Oxygen

    Rochester, MN

  2. A Study to Compare the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit

    Jacksonville, FL

  3. Study to Evaluate the Effects of Vitamin B3 Derivative on Bone, Skeletal, Muscle and Metabolic Functions in Aging

    Rochester, MN

  4. Cervical Spinal Cord Stimulation in Cerebral Vasospasm

    Jacksonville, FL

  5. A Study to Evaluate Patient Experience Comparing Tonic vs. Burst Spinal Card Stimulation for Chronic Pain

    Jacksonville, FL

  6. A Study Using Prothrombin Complex Concentrate versus Fresh Frozen Plasma for Post Cardiopulmonary Bypass Surgery Clotting Problems and Bleeding

    Rochester, MN

  7. A Study to Evaluate the Central Mechanisms of Sympathetic Neural Discharge

    Rochester, MN

  8. A Study of Oxygen Binding to Hemoglobin During Exercise and Hypoxia in Humans.

    Rochester, MN

  9. Tobacco Dependence Intervention Knowledge, Practices, and Attitudes among Registered Nurses

    Rochester, MN

  10. Response of Continuous Recombinant Antithrombin Infusion in Postcardiotomy ECMO Patients

    Rochester, MN

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